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At week 26, the difference in HbA1c reduction from baseline between TRESIBA administered at alternating times and insulin glargine U-100 was 0.17% with a 95% confidence interval of [0.04%
However, the study also found that the risk of gallbladder varied between different types of GLP-1 agonists and depended on the therapy duration and dosage
Blood pressure and lipid profiles may also change
Racing heartbeat
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